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Paired BM and PB concentrations of ADO and INO at baseline and at DARA treatment failure are shown for each patient, together with derived ADO/(ADO + INO) and INO/(ADO + INO) ratios and best response to DARA therapy (IMWG criteria)

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Finally, it has an antioxidant effect and it also plays a role in the learning and memory process as well as in the structure and support of the nervous system

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In the TRIUMPH-4 trial, participants on the 12 mg dose of retatrutide lost an average of 71.2 pounds over 68 weeks