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doi: 10.1056/NEJMc2107725 4 ZugastiIEspinosa-ArocaLFidytKMulens-AriasVDiaz-BeyaMJuanMet al

The exact symptoms can differ based on which valve is affected, but they generally include: Abnormal heart murmur Irregular heartbeat Chest pain Shortness of breath, especially when lying down or after physical activity Fatigue Dizziness or fainting Abdominal swelling Swollen feet or ankles Preventing Cardiovascular Complications From Medication Patients with cardiovascular issues often take multiple medications, sometimes prescribed by several different clinicians, without considering the potential for drug interactions and filled by different pharmacists

Placidi M, Di Emidio G, Virmani A, DAlfonso A, Artini PG, DAlessandro AM, et al

WaterColor and WaterOrientation VIDA extensions were applied to the results of SZMAP calculations to visualize the regions that favor polar and non-polar substituents