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636 , A74 (2020)

The reason why homocysteine is dangerous is because it damages cells and tissues of the arteries, triggers inflammatory reactions and enables cholesterol oxidation, which contributes to the build-up of atherosclerotic plaques the main culprits in cardiovascular disease (Kumar et al., 2017)

Similar to the BPC 157 effect on sphincters function, BPC 157 exhibited a particular anti-reflux effect in healthy (i.e., increase of pressure within lower esophageal sphincter, decrease of pressure within pyloric sphincter), while also rescuing sphincters failure (i.e., decreased pressure) in esophagitis rats (increase toward the normal values) (31, 32)

There are two main pathways for cysteine catabolism: one is via its enzymatic breakdown to produce H 2 S and organic intermediates that will serve as carbon sources, and the second is via oxidative metabolism through cysteine dioxygenase (CDO)