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Wu X, Liu H, Wang J, Zhang S, Hu Q, Wang T

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The oligodendroglial toxicity is mediated by a transporter-related mechanism involving the inhibition of cystine uptake, which results in glutathione depletion and cellular vulnerability to toxic-free radicals

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Concurrently, this compound rectified GOT2-mediated tryptophan/kynurenine metabolic imbalance, ultimately mitigating cardiac fibrosis and dysfunction

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