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Stepwise Strategies for Treatment of Asthma Novel 2019/2020 Global Initiative for Asthma (GINA) Treatment Strategy Background (The Basis for an Evidence Based Change in Treatment) Prior to 2019, the previous set of guidelines published by the Expert Panel Working Group at the NIH (EPR-3) in 2007 ( recommended that patients with the mildest form of intermittent asthma rely upon the occasional use of short acting beta-2 agonists (SABAs) for rapid relief or rescue from their periodic symptoms

Methylation levels were quantified as -values, representing the proportion of methylated signal relative to the total signal

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2019;11:234 Dong TS, Mayer E