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In malignant proliferating cells dominated by glycolysis, the upregulation of glutamine metabolism promotes energy metabolism via the modulation of TCA cycle and provides raw materials for lipid and amino acid delivery as well as biosynthesis of purines and pyrimidines, which ultimately promotes tumor growth by facilitating cell proliferation and inhibiting cell apoptosis ( The upregulation of glutamine metabolism has been extensively studied in many types of cancer and its very critical for the pathogenesis of cancers, which renders it a well-known target for cancer therapy

It comes from the leaves of the tea plant, Camellia sinensis

53 These findings suggest that SCFAs may exert a dual modulatory effect on macrophage activation

T/GUDCA, T/glycoursodexoycholic acid

The precise delivery, stimuli-responsive characteristics, and biomimetic design of nanomaterials markedly improve drug concentration at the lesion site and mitigate fibrosis, inflammation, and malignant tumor advancement by disrupting mechanical signaling pathways