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Morales A, Garca-Ruiz C, Miranda M, Mari M, Colell A, Ardite E, and Fernndez-Checa JC (1997)

Ethics approval for the use of NOD/LtJ mice was obtained from the Animal Care and Use Committee at the Institute of Laboratory, Guangzhou Medical University, with reference number G2023-147, 2/3/2023

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However, in the complex molecular processes that characterize tumorigenesis, iron also plays a central role in ferroptosis, a form of non-apoptotic regulated cell death characterized by the lethal accumulation of lipid peroxidation products and ROS derived from iron metabolism (362, 363)