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10.1016/j.redox.2021.102227 41 HayesJ

Future directions First, define exposureresponse with quantitative pharmacokinetics and, where possible, receptor-occupancy or target-engagement biomarkers to guide dose selection across tissues

[DOI] [PubMed] [Google Scholar] 238.Solomon SD, Skali H, Anavekar NS, Bourgoun M, Barvik S, Ghali JK, et al

Chronic sleep deprivation suppresses the same axis LR3 IGF-1 is supplementing, and cortisol elevation from chronic stress drives the protein-degradation pathways LR3 IGF-1 is suppressing