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Tang YJ, Wu W, Chen QQ, Liu SH, Zheng ZY, Cui ZL, et al

The NLX-112 group showed significant reductions in UDysRS) average sum scores at predefined time points after a levodopa challenge test on day 28 (end of uptitration phase) and 42 (end of stable dosing phase) on treatment as compared to placebo treated patients

In another study, RRBS was utilized to analyze DNA methylation changes in the TG4510 transgenic mouse model, which overexpresses the P301L mutant human tau proteina common tauopathy model in AD research (55)