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Gage NM, Juranek J, Filipek PA, Osann K, Flodman P, Isenberg AL et al

Traumatic brain injury induces region-specific glutamate metabolism changes as measured by multiple mass spectrometry methods

Methods Materials All chemicals including HPLC-grade solvents and high-purity metabolite standards were purchased from Sigma-Aldrich (St Louis, MO) unless noted otherwise

Our proposition is that the suboptimal glutathione levels associated with so many chronic diseases are not due to a cysteine undersupply but an impairment in one of the multiple control mechanisms of the GCL enzyme

Accumulation of p62/ SQSTM1 is associated with poor prognosis in patients with lung adenocarcinoma