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Description

Antibody-functionalized porous silicon nanoparticles for vectorization of hydrophobic drugs

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ASN Neuro 4 , e00093 (2012)

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Early NO-releasing systems, such as diazeniumdiolate-based DETA/NO polymers, demonstrated potent antibacterial activity but suffered from uncontrolled donor leaching and cytotoxicity 232

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While the aim of this article is not to review these and other considerations in detail, the box below represents a compilation of a few unanswered questions that could guide further academic and clinical discourse in this area

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The strong enrichment of amino acid biosynthesis (vra01230) and related pathways, viz., alanine, aspartate and glutamate metabolism (vra00250), arginine biosynthesis (vra00220), glycine, serine and threonine metabolism (vra00260), and cysteine and methionine metabolism (vra00270), indicates an adaptive accumulation of osmoprotective and stress-responsive amino acids

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