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NAC can inhibit ferroptosis by replenishing intracellular glutathione and supporting GPX4 activity, but its broad mechanism of action makes it difficult to attribute benefits specifically to ferroptosis inhibition ( Key hurdles for clinical translation of ferroptosis inhibitors include ( 5.2 Gut microbial modulators Understanding the role of gut microbiota in ferroptosis opens up exciting possibilities for new therapeutic strategies

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Those include: Anticoagulants , more commonly known as blood thinners, reduce the bodys ability to clot and increase the risk of serious bleeding

doi: 10.1007/s00401-016-1580-y 229 ShinoharaM.SatoN.KurinamiH.TakeuchiD.TakedaS.ShimamuraM.et al

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