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In terms of mechanism, astaxanthin can cross the bloodbrain barrier (Petri and Lundebye, 2007) to exert its antioxidant (Pan et al., 2017), anti-inflammatory (Zhang et al., 2017b), and neuroplastic effects on the brain

A 2008 follow-up in Inflammation Research characterized early functional recovery (days 14 post-transection) using the Achilles Functional Index, myeloperoxidase activity, and vascular index, and reported anti-inflammatory effects together with increased new vessel formation (Krivic et al., 2008)

ISSLS prize winner: repeated disc injury causes persistent inflammation

After that, 250 g/mL of AHMSNs@UOx, NH-AHMSNs@UOx, AHMSNs@UOx@SC or NH-AHMSNs@UOx@SC was added for a 12-h incubation

Meanwhile, epigenetic regulation of a gene usually requires more than one epigenetic event