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Have an active flare-up of eczema, a wound with broken skin, or an active infection in the area of application

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Systemic effects from topical application are rare but not impossible with very high concentrations or compromised skin barriers

20% of NB patients and drives half of the aggressive forms of the disease with poor outcomes ( MYCN transcriptional machinery, synthetic lethality, and destabilization of the MYCN protein (6, 7)

Tinned sardines and tuna provide moderate amounts (38 micrograms per 100 grams) and offer convenient, shelf-stable options