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The fusion between autophagosomes and lysosomes is driven by the coordinated action of two distinct soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complexes (STX17-SNAP29-VAMP8 and YKT6-SNAP29-STX7), tethering factors (e.g., the HOPS complex) and Ras-associated binding proteins (RABs) (e.g., Rab7) (81, 8689) ( Figure 1 , panel 4)

388 Notably, the two subtypes of neurons may play different roles in social and repetitive behaviours

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