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For this reason, the NIH has not established a tolerable upper intake level for B12

We order vitamin B12 and folate testing when a person with Down syndrome we are evaluating has symptoms described above, has a lab abnormality for which follow up testing of vitamin B12 and/or folate is indicated, or the person has a condition in which deficiency is common (e.g., celiac disease)

Researchers using DEXA scans or waist circumference measurements often see disproportionate reductions in trunk fat compared to peripheral fat during this phase

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Methylmalonic acid (MMA) is a blood test that seems to be a better measure of vitamin B12 deficiency than serum vitamin B12 level