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Methotrexate tablets for inflammatory conditions Sounds like 'meth-o-trex-ate' Key points about methotrexate Methotrexate is used to treat inflammatory conditions such as rheumatoid arthritis, psoriasis and Crohn's disease

These sites are cleaved by the AP endonuclease, APE1, and corresponding nucleotides are then located into the gap by a DNA polymerase through two different sub-pathways, to finally be ligated by a DNA ligase (Krokan and Bjoras, 2013)