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Chromatin immunoprecipitation (CHIP) CHIP assays were carried out strictly in accordance with the manufacturers operational guidelines (Qiagen, Dusseldorf, Germany)

(2017) 14:S4069

These data position aging as a major risk factor for the development of AF

71 Class A GPCRs can further be divided by function into aminergic, peptide, protein, lipid, melatonin, nucleotide, steroid, dicarboxylic acid, sensory, and orphan subgroups, 72 with their corresponding indications ranging from hypertension, cardiovascular diseases, and pulmonary diseases, to depression and psychiatric disorders

LOOCV cross-validation and permutation tests were performed to test the model with Q 2 and R 2 being used to assess the robustness of the model