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MITF can be regulated by different signalling pathways, including the cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signalling pathway [25], the stem cell factor (SCF)/c-kit mediated signalling pathway [26,27] and the wingless-related integration site (Wnt)/-catenin signalling pathway [28]

Stanislawski et al., 2017)

Because of these multiple modes of action, curcumin is used clinically to treat a wide variety of conditions and diseases, including arthritis, diabetes, depression, cognitive decline, and autoimmunity, to name just a few