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Through microbialinduced protein misfolding, immune dysregulation, and metabolic toxicity, the gut microbiome contributes to multiple molecular events that converge on neurodegeneration

doi: 10.1007/s10072-010-0267-8 15

In NSCLC patients on ICIs, elevated plasma taurolithocholic acid (TLCA) and glycochenodeoxycholic acid (GCDCA) correlated with improved outcomes

More importantly, we found that the levels of antioxidant factors GSH and SOD were decreased in SIRT4_KO mice, and the production of oxidative products and lipid peroxidation markers was increased, suggesting that SIRT4 was involved in inflammation and oxidative stress during SAP