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This indicates that sensory nerves in brown adipose tissue are likely to form a feedback loop with sympathetic nerves, coordinating sympathetic neurotransmitter thermogenesis, promoting sympathetic thermogenesis when ambient temperature or local tissue temperature is too low, and inhibiting sympathetic thermogenesis when the temperature is too high, thus adapting to ambient temperature (131, 132)

Frizziero A, Vittadini F, Barazzuol M et al (2017) Extracorporeal shockwaves therapy versus hyaluronic acid injection for the treatment of painful non-calcific rotator cuff tendinopathies: preliminary results

These data help researchers understand how gutbrain hormone systems interact and how those interactions affect appetite and metabolic readouts within controlled study designs

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