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The evolving landscape of obesity pharmacotherapy Nature Reviews Drug Discovery, 2026 1 Obesity pharmacotherapy has moved from weight loss drugs to cardiometabolic disease-modifying therapy Obesity is now framed as a chronic, relapsing, neuroendocrine-metabolic disease, not simply a lifestyle failure

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Combination approaches simultaneously address multiple bottlenecks, enabling faster overall progress through the repair cascade

Then, get them medical help right away by calling a nearby hospital [3]