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In hypothyroidism, particularly autoimmune forms, microbial alterations are dynamic and patient-specific

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While showing limited primary tumor suppression (~20%), it reduces metastatic lesion formation by nearly 70%, highlighting high mtDNA content as a critical driver of metastasis

Khidr HY, Hassan NF, Abdelrahman SS, El-Ansary MR, El-Yamany MF, Rabie MA (2023) Formoterol attenuated mitochondrial dysfunction in rotenone-induced Parkinsons disease in a rat model: role of PINK-1/PARKIN and PI3K/Akt/CREB/BDNF/TrKB axis