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This incretin effect is considerably attenuated in people with type 2 diabetes (see Figure 1), a loss that is even considered an early indicator of the disease, but it was observed that this deficit could be completely corrected by the continuous infusion of GLP-1 to diabetic patients

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This selective fat loss without muscle wasting makes the peptide particularly attractive for individuals seeking to improve body composition rather than simply reduce body weight

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Symptoms may include: Constantly feeling tired or chronic fatigue Muscle aches and weakness Joint pain Difficulty breathing or shortness of breath Feeling dizzy Poor memory Inability to concentrate well Mood changes, like increased depression and anxiety Having abnormal heart problems, such as palpitations Poor dental health, including bleeding gums and mouth sores Digestive problems like nausea, diarrhea or cramping A poor appetite A more serious deficiency can also cause a form of anemia called pernicious anemia, a serious condition that can cause memory loss, confusion and even long-term dementia