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Reported adverse reactions include nausea, difficulty breathing, and, in rare cases, serious conditions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and renal dysfunction

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The resulting GSH or homoglutathione (-L-glutamyl-L-cysteinyl--alanine) conjugates were usually much less toxic and more water-soluble than the original xenobiotics (Brown and Neighbors, 1) (Bartling et al., 2002