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B.ArentC

10.1126/science.1523409

These cells sit in the connective tissue beneath the skin, loaded with granules containing histamine, heparin, and various enzymes

10.1007/s00432-018-2740-3 24

Because specific vitamins and minerals work antagonistically to one another, consuming large amounts of isolated supplements like B1 (thiamine) can contribute to a deficiency in vitamin B6 over time