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143B cells were plated in 12-well plates at a density of 3 10 5 cells/well and subsequently cultured for 12 h

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Arch Neurol 56:12411246 Vermeiren Y, Le Bastard N, Clark CM, Engelborghs S, De Deyn PP (2011) Serum glutamine synthetase has no value as a diagnostic biomarker for Alzheimers disease

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In addition, it was recognized that glutamate/glutamine cycle is a major energy source for tumor cells, including brain tumors (Tardito et al., 2015)

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