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The trial proceeded without reported toxicity, and no lethal dose threshold (LD1) was ever established in subsequent safety testing meaning researchers administering the compound could not find a dose that caused death in even 1% of test subjects across the animal model safety work that preceded and followed the human study

Clinical Ophthalmology , 2007

Since efferocytosis is a crucial function of pro-resolving macrophages, we then compared the ability of these polarized populations to clear apoptotic cells