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Glanbia plc Ireland Asia Pacific 1

200 Sequencing results indicate that Dact3-As1 in gastric cancer tissue might originate from fibroblasts, and Dact3-As1 enters gastric cancer cells via exosomes secreted by fibroblasts and induces ferroptosis by decreasing the levels of GPX4 and SLC7A11, thereby increasing the sensitivity of gastric cancer cells to oxaliplatin

This makes cross-centre replication and calibration essential and strengthens the case for standardised reference materials, inter-laboratory proficiency testing, and consistent reporting of protocol variables that plausibly drive variance [462, 483]