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[DOI] [PubMed] [Google Scholar] 39.Xie Y, McGill MR, Dorko K, Kumer SC, Schmitt TM, Forster J, Jaeschke H

1 Mechanism of apoptosis, necrosis, necroptosis and autophagy

Metformin treatment with concentrations of 10, 25, and 50 M significantly restored chondrocyte viability suppressed by H 2 O 2 exposure, and 50 M metformin was chosen for further studies (Fig

However, the clinical use of aptamers is limited by their susceptibility to degradation by nucleases and possible renal clearance, both of which shorten their therapeutic window