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In trabeculectomy samples, hypomethylation of Alu elements was noted across all glaucoma subtypes, while hypermethylation of HERV-K was specific to primary open-angle glaucoma patients, both alterations are associated with TM fibrosis and contribute to increased IOP (Chansangpetch et al., 2018)

Asthma or history of respiratory conditions

Immune Checkpoint Inhibitors (ICIs) activate immune cells and restore their tumoricidal potential, making them highly efficacious cancer therapies

Nat Rev Rheumatol (2012) 8:65664

Castejon et al., 2021), oral and intravenous GSH (Cazzola et al., 2021), and sublingual and/or oral liposomal GSH administration (Schmitt et al., 2015