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The predicted P eff value for D-NIe-Tyr-Ile-NH-(CH 2 ) 5 -CONH 2 (1.53) is intermediate between the predicted P eff values for enalapril (1.25) and piroxicam (2.14), two orally bioavailable drugs

This review highlights that given the robust preclinical evidence and high public interest, there is a critical need for well-designed human trials to assess the safety, efficacy, and clinical utility of BPC-157 in musculoskeletal medicine

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This screening should be thorough and appropriate for individual patient risk factors and demographics