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[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Kellenberger, E., Kuhn, I., Schuber, F

Nanomedicines have the potential to inhibit local tumor recurrence and distant metastasis after surgery

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IGF-1 LR3 has been used extensively in this context precisely because its extended half-life allows sustained receptor activation in cell culture and in vivo models without the impractical dosing frequency that native IGF-1 would require