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Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain

High-dose omega-3 supplementation can reduce triglycerides by 20-30% when taken at therapeutic doses of 4 grams daily

Moreover, improvements in gut barrier integrity and reductions in systemic inflammation have been observed

To transform preliminary findings into robust clinical guidance, future research must prioritize methodological rigor, targeted populations, and mechanistic clarity