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Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations E-GPx: extracellular glutathione peroxidase C-GPx: cellular glutathione peroxidase GPx: selenium-dependent glutathione peroxidase ROS: reactive oxygen species t-BuOOH: tert-butyl hydroperoxide GAPD: glyceraldehyde-3-phosphate dehydrogenase FiO2: fraction of inspired oxygen References Quinlan T, Spivack S, Mossman BT 1994 Regulation of antioxidant enzymes in lung after oxidant injury

Redox imbalance and hypoxia-inducible factors: A multifaceted crosstalk

Notably, core fucosylated MSLN (Cf-MSLN) was found to be reduced in tumor tissues and serum compared to healthy controls, suggesting its potential as a more specific biomarker for pancreatic cancer than total MSLN levels