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Investigations in cultured macrophages, human monocytes and mouse models of inflammatory diseases demonstrated that BHB inhibits NRLP3 inflammasome activation through a mechanism that involves blocking potassium efflux and preventing ATP-induced ASC oligomerization, which are both needed for inflammasome assembly (43)

The author thanks the past and present members of his laboratory for outstanding work over the past decade, Andrea Blitzer, M.D

[DOI] [PubMed] [Google Scholar] 58.Liebmann J.E., Hahn S.M., Cook J.A., Lipschultz C., Mitchell J.B., Kaufman D.C

They found that obese individuals in the processes of dieting exhibited a 50% reduction of T4 into the cell and a 25% reduction of T3 into the cell

PMID: 32232832 Anal Chem High-Throughput Reactive Desorption Electrospray Ionization Mass Spectrometry for Targeted Derivatization and Analysis of Poorly Ionized Small Molecules