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doi: 10.1016/j.freeradbiomed.2023.06.009 32 Le GalKWielCIbrahimMXHenricssonMSayinVIBergoMO

Previous investigations have highlighted elevated NNMT expression in the liver and white adipose tissue (WAT) of diabetic mice and obese, with evidence suggesting that downregulating NNMT expression can mitigate diet-induced IR and obesity (Kraus et al., 2014

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NAD+ serves as an essential coenzyme for hundreds of enzymatic reactions, including those involved in energy production, DNA repair, and cellular signaling