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Increased Interleukin-8 (IL8)-CXCR2 Signaling Promotes Progression of Bone Marrow Fibrosis in Myeloproliferative Neoplasms

Introduction Mitochondria are double membrane organelles which are actively involved in a multitude of cellular activities such as energy production in the form of adenosine triphosphate (ATP), intracellular Ca 2+ signalling, generation of reactive oxygen species (ROS), and catalysis of metabolites ( In healthy individuals, these processes are well balanced