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doi: 10.1001/archneurol.2010.227 116 DreherSIGrubbaPvon ToerneCMoruzziAMaurerJGojTet al

Full growth hormone administration can stimulate cortisol production through various mechanisms, and elevated cortisol is well-documented to increase appetite, particularly for high-calorie comfort foods, and promote abdominal fat accumulation

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The methyl group helps stimulate serotonin creation, which is a neurotransmitter responsible for mood support