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As an NADPH-selective enzyme, FSP1 suppresses ferroptosis by oxidizing NADPH

2019;10 doi: 10.3389/fimmu.2019.00277

In the normal state when gluatione stores are adequate gluathione exerts a negative feedback inhibition on the enzyme -glutamyl cysteine synthase which regulates the cycle

For the protein solutions the excitation wavelength was fixed at 295 nm (maximum absorbance = 0.10 OD) and emission spectra were recorded between 310 and 410 nm with an emission slit width of 2.5 nm