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Availability: InStock
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Description

Abstract Inflammatory bowel disease (IBD) is characterized by chronic intestinal inflammation, strongly influenced by gut microbiota dysbiosis, barrier dysfunction, and immune imbalance

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In a study, researchers predicted the MGMT inhibitory activity of 134 base analogs with QSAR and found some purine analogs, such as O6-benzyl-8-bromo-guanine, O6-thenyl-guanine, and O6-(3-aminomethyl) benzyl-guanine which were potent MGMT inhibitors