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Therefore, understanding whether IF can mitigate these factors by improving both inflammatory and oxidative stress markers, as well as liver enzyme profiles, could offer a novel, non-pharmacological strategy for managing RA and its associated metabolic complications in this vulnerable population

The study protocol was approved by the Ethics Committee of Minzu University of China and followed the guidelines of the Declaration of Helsinki

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The results showed that the overexpression of ATP6AP1L gene with pcDNA3.1-GST DAF -ATP6AP1L and pcDNA3.1-GST CEAM7 -ATP6AP1L could significantly inhibit the proliferation of K-562 cells compared with the control cells transfected with empty vectors, pcDNA3.1-GST DAF, and pcDNA3.1-GST CEAM7 , respectively