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Frequency depends on your treatment goals

Eur J Immunol (2016) 46:74251

However, Nectapharma has designed the formula to be more user-friendly and gentle by incorporating Dual Encapsulation technology, which controls the release of retinal so the skin receives it gradually and continuously, helping to reduce irritation

Figure 9 Earlier research has indicated that the disturbance in the balance of cytokines is implicated in the initiation and advancement of IBD, CD and UC (198)