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For this reason, it is relevant to understand the environmental constraints that allowed such protective defense enzymes to evolve

In some research contexts, observations have included mild and transient tolerability-related effects such as: Headaches Nausea Stimulation-related observations Temporary injection-site irritation or localized skin-response variability Research conditions, concentration ranges, dosage ranges, hydration status, administration frequency, and protocol structure may influence tolerability observations across experimental settings

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Chen S.Y., Chen C.J., Tsai W.Y., Ahsan H., Liu T.Y., Lin J.T., Santella R.M

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