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Description

It is possible that these variants have impaired folding and localisation, although R169W has previously been shown to localise normally to the membrane 53

MC: Writing original draft, Writing review and editing

As an endogenous peptide responsive to exercise and nutrient cues, it regulates pathways involved in energy homeostasis and cellular adaptation

2017;7(3 Suppl):95S-115S

It also acts as an antioxidant in brain tissue and peripheral nerves, protecting against the oxidative stress that accumulates with heavy training loads and aging