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Active DNA demethylation: many roads lead to Rome

Calo, L., Wegrzynowicz, M., Santivaez-Perez, J., & Grazia Spillantini, M

Preferential accumulation at injury sites suggests active homing mechanisms or increased vascular permeability and tissue binding at sites of damage, though specific mechanisms governing injury-site localization remain under investigation

doi: 10.1016/j.arr.2020.101036 16 MargaritelisNVPaschalisVTheodorouAAKyparosANikolaidisMG

This matters because your body naturally makes less collagen as you age and the collagen you have left breaks down faster, so supporting that process directly is more useful than masking the surface