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Source sample type (that is, bone marrow versus peripheral blood) was treated as an unwanted source of variation (batch effect) and removed before downstream analysis

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Mercury intrusion porosimetry revealed substantial variability in pore size distributions among membranes with identical 0.2 m ratings, and LNP filtration capacity correlated strongly with the experimentally determined mean pore size Dual-layer membranes, such as the 0.8/0.2 m Sartopore 2 XLG, markedly improved LNP filtration capacity and reduced fouling through the inclusion of an integrated prefilter layer