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Venlafaxine at doses above 150 mg/day produces clinically meaningful NET inhibition

The maximum concentrations (C max ) of each dose were 12.3, 48.9, and 141 ng/ml, respectively, and the AUC 0t values were 75.1, 289, and 1930 ng min/ml, respectively

Additionally, any speckles smaller than 10 pixels in 2D space (white) were also eliminated