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These secondary diagnoses can significantly impact MS-DRG assignment and risk adjustment

It was concluded that, in comparison with controls, patients with ME/CFS have a higher resting heart rate, lower maximal/peak heart rate, higher heart rate responses to head-up tilt testing and moving from sitting to standing, and a lower heart rate at submaximal exercise threshold

For instance, recent work published by Stuart et al

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Eric Topol (31:14): I think that's a vital point you're making because the success of a clinical trial here in a clinical syndrome that is mosaic with lots of different types of pathways