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Clinical literature documents anaphylaxis cases following parenteral vitamin B-12 administration, particularly with cyanocobalamin formulations

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Support Your Health with Everlywell Vitamin B12 plays an important role in energy production, nerve function, and red blood cell formation

In a long-term randomized, double-blind, placebo-controlled study among sufferers of cerebrovascular accidents at high risk of depression, daily supplementation with 2 mg of folic acid, 25 mg of vitamin B6, and 500 g vitamin B 12 significantly lowered the risk of major depressive episodes during a seven-year follow-up period compared to placebo (111)